Imaging of the Brain in Psychiatry and Related Fields - Hardcover

In the last two decades imaging of the brain, or neuroimaging, has become an integral part of clinical and research psychiatry. This is due to recent advances in computer technology, which has made it relatively easy to generate brain images representing structure and function of the central nervous system. Currently used clinical diagnostic imaging modalities, such as X-ray computed tomography (CT) and magnetic resonance imaging (MRI) , provide predominantly anatomic information. CT images reflect X-ray attenuation distribution within the brain, whereas MRI signals depend primarily on proton sensitivity and tissue relaxivity. The chapter "Structural Imaging Methods" reviews CT and MRI studies on schizophrenic and affective disorders and degenera­ tive central nervous system diseases. The impact of fast three­ dimensional (3-0) imaging and the automatic transfer from 3-D elements in the brain to artificial diagrams based on this information is considered. Since the original report of the findings of Ingvar and Franzen in 1974 and the introduction of regional cerebral blood flow (rCBF) measurements, single photon emission computed tomography (SPECT) has been gaining acceptance as one of the major imaging techniques, and it is available in most nuclear medicine depart­ ments. The section "Functional Imaging Methods (Cerebral Blood Flow - CBF, Single Photon Emission Computerized Tomography - SPECT)" describes rCBF studies with the 133Xe inhalation method utilizing a 254 detector system and rCBF images measured by SPECT using the tracer 99mTc-HMPAO.

This book represents a review of the state of the art, most recent developments, and future trends in neuroimaging in psychiatry, neuropsychiatry, neurology, neuroradiology, nuclear medicine and related disciplines. The articles by recognized authorities in the field of neuroimaging will focus on results gained by CT, MRI, CBF, SPECT, PET, CET (Computed Electroencephalography), MEG (Magnetencephalography), Behavioural Imaging (Imaging of neuropsychological data) and BCI (Biochemical Imaging - topgraphic mapping of biochemical data, immunocytochemistry, autoradiography and topography of drug actions). The contributions in this volume range from discussions of methodological and clinical aspects to more philosophical discourses of approach. Here, different ways in which neuroimaging can be used clinically are outlined. The information presented represents a major step in bringing the modern advances in neuroimaging to the psychiatrists, neurologists, neuropsychologists and all other working in the field of neuroimaging who will profit from them.