Apolipoprotein E and Alzheimer's Disease (Research and Perspectives in Alzheimer's Disease) - Hardcover

There is genetic evidence that the type 4 allele of the apolipoprotein E gene is a major, susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after 60 years of age. This work presents the results concerning the implications of apoliprotein E on the genetics, cell biology, neuropathology, biochemistry and therapeutic management of Alzheimer's disease.

There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.